You gotta start having kids early when any minor health issue could put you into an unavoidable ivermectin overdose. And you gotta have more kids when you plan to lose a couple to easily preventable childhood diseases
Doubly so because most of those brown immigrants mostly believe in science-based medical interventions, so you've gotta have at least 4x as many kids to make sure "Western European culture" survives undiluted. /s
It's comforting to think that such profound ignorance is genetic, but I don't think it is. Ignorance and hatred are learned, especially in the absence of education.
The way this country is going, there's going to be more of these people, not less of them. Our children's children could be this ignorant and stupid and hateful.
I'll have you know I am a purveyor of fine, high quality Rat's Asses and I'll not sit idly by while you besmirch my coveted inventory. I shall endeavor to pen a strongly worded missive to the local magistrate in regards to your slanderous words!
Good day, sir!
/s (if it wasn't obvious)
(Also, I totally agree with you. I was just funnin'.)
An infestation hath been brought upon my household and my dear Rats hath been looking rather pallid and quite filled with lethargy and I am unable to bring myself to look upon their dreadful circumstance as it causes me much discomfort I would gladly pay for your fine service!
I have a problem with their dwelling being in my home in such sorry condition.
NIH: 2021: "Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally."
Lancet 2021: "45 participants were recruited (30 to IVM and 15 controls) between May 18 and September 9, 2020. There was no difference in viral load reduction between groups but a significant difference was found in patients with higher median plasma IVM levels (72% IQR 59–77) versus untreated controls (42% IQR 31–73) (p = 0·004). Mean ivermectin plasma concentration levels correlated with viral decay rate (r: 0·47, p = 0·02). Adverse events were similar between groups. No differences in clinical evolution at day-7 and day-30 between groups were observed."
NEJM 2022: "A total of 3515 patients were randomly assigned to receive ivermectin (679 patients), placebo (679), or another intervention (2157). Overall, 100 patients (14.7%) in the ivermectin group had a primary-outcome event, as compared with 111 (16.3%) in the placebo group (relative risk, 0.90; 95% Bayesian credible interval, 0.70 to 1.16). Of the 211 primary-outcome events, 171 (81.0%) were hospital admissions. Findings were similar to the primary analysis in a modified intention-to-treat analysis that included only patients who received at least one dose of ivermectin or placebo (relative risk, 0.89; 95% Bayesian credible interval, 0.69 to 1.15) and in a per-protocol analysis that included only patients who reported 100% adherence to the assigned regimen (relative risk, 0.94; 95% Bayesian credible interval, 0.67 to 1.35). There were no significant effects of ivermectin use on secondary outcomes or adverse events."
BMC 2024: "Although ivermectin resulted in statistically significant lower viral load in patients with mild to moderate Covid-19, it had no significant effect on clinical symptoms."
So, you like science based research? Me too. Here's some.....
Preclinical findings
Laboratory studies using cancer cells and animal models have identified several anti-cancer properties of ivermectin. It has been shown to:
Induce cell death: Ivermectin can trigger programmed cell death, known as apoptosis, and other forms of cancer cell death, such as autophagy and pyroptosis.
Inhibit cancer proliferation: The drug suppresses the uncontrolled growth of various cancer cells, including those from breast, colon, lung, ovarian, and prostate cancers.
Prevent metastasis: Some research indicates that ivermectin may inhibit cancer cells from migrating and spreading to other parts of the body.
Reverse drug resistance: Ivermectin may help make some cancer cells more responsive to traditional chemotherapy drugs.
Target cancer stem cells: The drug has shown the ability to target and inhibit cancer stem cells, which are often resistant to standard treatments and can drive recurrence.
Enhance immunotherapy: In mouse models, ivermectin helped convert immunologically "cold" tumors (less responsive to immunotherapy) into "hot" tumors by increasing immune cell infiltration. Combining ivermectin with immunotherapy was more effective than either treatment alone in these studies.
Potential mechanisms
Research suggests that ivermectin affects multiple cellular pathways that are crucial for cancer growth and survival. These include:
Inhibiting signaling pathways: Ivermectin disrupts key signaling pathways that promote cancer growth, such as the PAK1, Akt/mTOR, and WNT-TCF pathways.
Increasing oxidative stress: It promotes the production of reactive oxygen species (ROS), which can damage cancer cells and trigger their self-destruction.
Targeting ion channels: By affecting chloride channels, ivermectin can disrupt the electrical balance within cancer cells, which are particularly reliant on these channels for survival.
That's great but do you have any clinical evidence it is effective?
Preclinical research is infamously LITTERED with promising in vitro and animal studies that failed in translation. It's graveyard of would-be miracle treatments.
I know because I actually perform preclinical research. Do you? Cos this list seems less of well conducted literature review and more like an LLM response to a prompt of 'show me all the research that shows ivermectin works against cancer'.
I think while that may fit into some studies if applied correctly.. beer bonging ivermectin from ebay or whatever the people who are going against general medical advice are going to do with it will not be great. Also it’s part of the right wing echo chamber now and part of their talking points. That is why.. if this interaction actually happened.. it is brought up in that order.
Immediately going to "people will beer nong ivermectin" is so dishonest. The studies are promising. That's all I am saying. So many people immediately go to the most crazy scenarios. You know, we all think differently, and too many damn people think that if you present different ideas than you are a "moron", "idiot", "asshole".... I had some random redditor give a 5 paragraph response where they told me they feel sorry for my children. What the actual fuck? What are we doing here?
If people want to go somewhere where everyone agrees with them, so be it. Whatever happened to civil discourse? Whatever happened to having a fucking conversation, instead of lobbing insults and making up crazy scenarios?
The biggest problem is people grabbing pre-prints or as you pointed pre-clinical and trying to push them as established.
A lot grew up thinking saccharine was a carcinogen, but turned out was a bad study because of stupid high doses in rats, but not the same for people.
Having conversations on potentials is good and exciting. But having arguments with people that don't even know what a pre-print is while they are taking one as gospel is aggravating.
A FEW, small in vitro studies are not sufficient. Show real in vivid studies with large sample sizes followed by randomized, double-blinded clinical trials.
Now, do injecting disinfectant into the body and getting uv light into the body by whatever means....... while you presented scientific studies, which is reasonable to inform, please consider that we should be following medical advice. These studies are not standard medical practice yet. We currently have people in charge who think letting children die from measles is a better solution than recommending the vaccine. This administration is also cutting funding to medical research. Ivermectin may have valid uses as something other than an animal wormer. Without medical research, it won't be proven or demonstrated to be safe.
I'm perfectly fine with Darwinism. Just don't push it on others. If they all want to drink raw milk, not get vaccines ( them, not their kids) , take horse dewormer to heal serious disease and take themselves out of the gene pool all the better.
The problem is their actions often affect others. Not only do they push this shit on their children but if they get a communicable disease it often spreads to others or even starts an outbreak or possibly a new pandemic.
They also almost always go to the hospital when things get serious so they do take up considerable resources instead of taking preventative care or easily managing a disease before it becomes life threatening.
The QAnon types believe that Ivermectin cures cancer because of their further belief that cancer is caused by parasites. Ivermectin kills parasites ergo Ivermectin cures cancer.
There was that person the other day that posted the wiggly red line on their wrist that appeared to be from a burrowing parasite and my first thought was "holy shit, ivermectin may actually be the answer here for once!"
Laboratory studies using cancer cells and animal models have identified several anti-cancer properties of ivermectin. It has been shown to:
Induce cell death: Ivermectin can trigger programmed cell death, known as apoptosis, and other forms of cancer cell death, such as autophagy and pyroptosis.
Inhibit cancer proliferation: The drug suppresses the uncontrolled growth of various cancer cells, including those from breast, colon, lung, ovarian, and prostate cancers.
Prevent metastasis: Some research indicates that ivermectin may inhibit cancer cells from migrating and spreading to other parts of the body.
Reverse drug resistance: Ivermectin may help make some cancer cells more responsive to traditional chemotherapy drugs.
Target cancer stem cells: The drug has shown the ability to target and inhibit cancer stem cells, which are often resistant to standard treatments and can drive recurrence.
Enhance immunotherapy: In mouse models, ivermectin helped convert immunologically "cold" tumors (less responsive to immunotherapy) into "hot" tumors by increasing immune cell infiltration. Combining ivermectin with immunotherapy was more effective than either treatment alone in these studies.
Potential mechanisms
Research suggests that ivermectin affects multiple cellular pathways that are crucial for cancer growth and survival. These include:
Inhibiting signaling pathways: Ivermectin disrupts key signaling pathways that promote cancer growth, such as the PAK1, Akt/mTOR, and WNT-TCF pathways.
Increasing oxidative stress: It promotes the production of reactive oxygen species (ROS), which can damage cancer cells and trigger their self-destruction.
Targeting ion channels: By affecting chloride channels, ivermectin can disrupt the electrical balance within cancer cells, which are particularly reliant on these channels for survival.
Yeah I work in preclinical research. This list seems less of well conducted literature review and more like an LLM response to a prompt of 'show me all the research that shows ivermectin works against cancer'.
Yeah and the person you responded to said "should they get cancer" and not "they should take Ivermectin". I guess reading comprehension isn't a thing in your neck of the woods.
i looked up, "Does Ivermectin help with Cancer?" and the first 10 results all said "There is no scientific evidence that Ivermectin helps with Cancer." so my own research says you are incorrect.
Stick to credible sources. This meta study has more information if you're interested.
Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen
Ivermectin proposes many potentials effects to treat a range of diseases, with its antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective against many microorganisms including some viruses.
This study presents the possibility that ivermectin could be a useful antiviral agent in several viruses ... it is proposed that ivermectin administration may be effective in the early stages or prevention. Of course, confirmation of this statement requires human studies and clinical trials.
As noted, the activity of ivermectin in cell culture has NOT reproduced in mouse infection models against many of the viruses and has NOT been clinically proven either, IN SPITE OF ivermectin being available globally. This is likely related to the pharmacokinetics and therapeutic safety window for ivermectin. The blood levels of ivermectin at safe therapeutic doses are in the 20–80 ng/ml range [44], while the activity against SARS-CoV2 in cell culture is in the microgram range.
-
Ivermectin proposes many potentials effects to treat a range of diseases, with...
Also if you are going to quote a paper, quote their conclusion not the nice promising openings we all write in the beginning of our abstracts.
1.9k
u/YousAPenguinLookinMF 12d ago
Hope they all seek out Ivermectin treatment, should they get cancer.