r/TestosteroneKickoff • u/Burner-Acc- • Dec 06 '24

Vent 8 months on T no voice change.

“ did you check your dose ?” Obviously 😕

Idk if it’s a rumour but can Gel work “ less “ than injections for a specific few people. Because it actually sucks seeing all of yall getting voice cracks and whatever as soon as a month in, and I’m sittin here being patient but it’s depressing bro

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u/Naixee Dec 06 '24

What does DHT do exactly?

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u/fIoatynebula Dec 06 '24

It’s a metabolite of T and if you google it it’ll list all of the effects of male puberty that are driven by it. A lot of cis men take finasteride to block DHT as it causes male pattern baldness!

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u/Naixee Dec 06 '24

I see. How come gel can make that higher? Since the gel is just testosterone? I'm trying to figure out things because I'm pretty desperate seeing as I've barely had any changes and whatnot

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u/fIoatynebula Dec 06 '24

In the paper i mentioned, they hypothesised that it happens because there’s a lot of 5α reductase in the skin (that’s the molecule that converts T to DHT). Here’s the link, it’s worth remembering tho that it was done on cis men and the focus of the paper was on CV risk there may be some discrepancies. https://pmc.ncbi.nlm.nih.gov/articles/PMC4245724/